[Beowulf] Re: overclocking with liquids

David Mathog mathog at caltech.edu
Mon Sep 24 12:15:09 EDT 2007


richard.walsh at comcast.net wrote

> After a minute the 
> mouse was running around again and seemed no worse off.

"Seemed" being the key word here.  If memory serves the biggest
problem with being immersed in these types of oxygen carrying inert
fluids is that they leak into the body, presumably through the lungs. 
Eventually that gunk ends up in the liver which becomes cirrhotic.

Since the time scale was so short that really wasn't much of a safety
demonstration.  There are lots of things that could be injected into a
mouse and it would run around happily for a couple of hours and then be
dead in a few days.  At the more extreme toxic end of the spectrum, 
here are a couple most people have heard of:  ricin and alpha-amanitin. 

Regards,

David Mathog
mathog at caltech.edu
Manager, Sequence Analysis Facility, Biology Division, Caltech
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